While studying the regulation of flowering in Arabidopsis thaliana, we uncovered a family of proteins that play multifaceted roles in gene expression via a common mechanism: slowing down the progression of RNA polymeraseII
Tools for the analysis and integration of high throughput data
Ensuring that one gene's transcription does not inappropriately affect the expression of its neighbors is a fundamental challenge to gene regulation in a genomic context. In plants, which lack homologs of animal insulator proteins, the mechanisms …
BDR negative elongation factors protect the genome from transcriptional interferences
BDR negative elongation factors protect the genome from transcriptional interferences