I obtained my diploma of engineering in agronomy at Agrocampus Ouest together with an MSc in Biochemistry and Genetics applied to Animal Science from Univ. Rennes II in 2000. Then, I worked on transcriptional regulations by the nuclear receptors PPARalpha and RXR at INRA Pharmacology and Toxicology research unit (supervisor T. Pineau) and obtained my PhD in biology in 2007 at Toulouse III University.
I was appointed as a research engineer at INRA during my PhD (2004) and co-directed the group of Integrative Toxicology & Metabolism for 4 years (2008-2011). Next, I created the GeT-TriX transcriptomic facility at INRA ToxAlim (2011-2013). During these years, I led significant research projects that contributed to the development of ToxAlim.
In 2013-2015, I joined the group of Olivier Cuvier at the Center for Integrative Biology, where I studied chromatin organization and transcription in Drosophila cells using various genome-wide approaches based on NGS.
In 2015-2017 I was awarded an Agreenskills+ fellowship, and joined the group of Scott Michaels at Indiana University Department of Biology to decipher the role of a new family of negative transcription elongation factors on RNA polymerase II processivity, chromatin organization and gene expression.
In 2017-2019, back at INRA Toxalim, I joined the BioToMyc group of Isabelle Oswald where I initiated a project aimed at elucidating the role played by transcription elongation factors on the regulation of gene clusters involved in the synthesis of mycotoxins.
In 2019-2020, I joined the lab of Pr Craig Pikaard at Indiana University where I worked on long read sequencing to assemble the ribosomal DNA regions of the genome of Arabidopsis thaliana.
In dec 2020, I moved back to France and joined the Fruit Biology and Pathology department at INRAE. My first aim is to set up tools to analyze how changes in the epigenome of endoreduplicated cells contribute to the growth of tomato fruit.
Throughout my career, I have balanced biology with bioinformatics and biostatistics and gained experience in the production and analysis of different types of high throughput data.
PhD in Pharmacology, 2007
Université de Toulouse
MSc in Animal Biology & Production (Applied Genetics and Biochemistry), 2000
Université de Rennes
MSc in Agricultural Engineering (Ingénieur Agronome), 2000
Agrocampus Ouest / Ecole Nationale Supérieure d'Agronomie de Rennes
Role of nuclear receptors in the regulation of hepatic metabolism
PPARalpha-mediated transcriptional regulations