Endoreduplication, during which cells increase their DNA content through successive rounds of full genome replication without cell division, is the major source of endopolyploidy in higher plants. Endoreduplication plays pivotal roles in plant growth …
- BDR proteins repress expression of the floral repressor, FLC - BDR proteins physically interact with the autonomous pathway protein FPA - BDR-repressed genes have high levels of Pol II occupancy, despite low mRNA levels - Gene repression by BDR may involve the inhibition of transcription elongation
Ensuring that one gene's transcription does not inappropriately affect the expression of its neighbors is a fundamental challenge to gene regulation in a genomic context. In plants, which lack homologs of animal insulator proteins, the mechanisms …