- BDR proteins repress expression of the floral repressor, FLC - BDR proteins physically interact with the autonomous pathway protein FPA - BDR-repressed genes have high levels of Pol II occupancy, despite low mRNA levels - Gene repression by BDR may involve the inhibition of transcription elongation
- The 7SK snRNA is dispensable for cell proliferation under standard growth conditions - After UV exposure, 7SK/P-TEFb is needed for proper stress response and cell survival - P-TEFb extracted from 7SK/P-TEFb triggers UV-induced general RNAPII pause release - P-TEFb from 7SK/P-TEFb supports activation of important UV-responsive genes
Transcription by RNA polymerase II in the context of chromatin
Gene expression regulation during endoreduplication in the pericarp of tomato fruit
Ensuring that one gene's transcription does not inappropriately affect the expression of its neighbors is a fundamental challenge to gene regulation in a genomic context. In plants, which lack homologs of animal insulator proteins, the mechanisms …
Visit [GeneNeighborhood on github](https://github.com/pgpmartin/GeneNeighborhood)
Generating random genome annotations For different purposes, I often need to create random gene/features annotations. I usually need these annotations as a GRanges object (see the GenomicRanges package).
I searched a bit on the internet but couldn’t really find what I was looking for.
GGally is an extension of ggplot2. I use it mainly as a replacement/refinement of pairs in base R.
Here, I want to replace the default scatter plot used to compare 2 continuous variables with something nicer, especially adapted to plotting large number of points.