elongation

- BDR proteins repress expression of the floral repressor, FLC - BDR proteins physically interact with the autonomous pathway protein FPA - BDR-repressed genes have high levels of Pol II occupancy, despite low mRNA levels - Gene repression by BDR may involve the inhibition of transcription elongation

Ensuring that one gene's transcription does not inappropriately affect the expression of its neighbors is a fundamental challenge to gene regulation in a genomic context. In plants, which lack homologs of animal insulator proteins, the mechanisms …