Publications

E Tourdot, PGP Martin, E Maza, JP Mauxion, A Djari, F Gevaudant, C Chevalier, J Pirrello, N Gonzalez (2024). Ploidy-specific transcriptomes shed light on the heterogeneous identity and metabolism of developing tomato pericarp cells. Plant J. 2024 May;118(4):997-1015..

PDF Dataset Project DOI Pubmed

X Yu*, PGP Martin*, Y Zhang, JC Trinidad, F Xu, J Huang, KE Thum, K Li, S Zhao, Y Gu, X Wang, SD Michaels, * co-first authors (2021). The BORDER family of negative transcription elongation factors regulates flowering time in Arabidopsis. Curr Biol. 2021 Dec 6;31(23):5377-5384.e5..

PDF Code Dataset Project DOI Pubmed

MT Parker, K Knop, V Zacharaki, AV Sherwood, D Tome, X Yu, PGP Martin, J Beynon, SD Michaels, GJ Barton, GG Simpson (2021). Widespread premature transcription termination of Arabidopsis thaliana NLR genes by the spen protein FPA. eLife. 2021 Apr 27;10:e65537..

PDF Project DOI Pubmed

C Studniarek, M Tellier, PGP Martin, S Murphy, T Kiss, S Egloff (2021). The 7SK/P-TEFb snRNP controls ultraviolet radiation-induced transcriptional reprogramming. Cell Reports. 2021 Apr 13;35(2):108965..

PDF Project DOI Pubmed

PGP Martin, V Dupouy, J Leghait, T Pineau, A Polizzi, F Lasserre, BB Roques, C Viguié (2020). Transcriptomic modifications of the thyroid gland upon exposure to phytosanitary-grade fipronil: Evidence for the activation of compensatory pathways. Toxicol Appl Pharmacol. 2020 Jan 15;389:114873..

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X Yu*, PGP Martin*, SD Michaels, * co-first authors (2020). BORDER proteins protect expression of neighboring genes by promoting 3' Pol II pausing in plants. Nat Commun. 2019 Sep 25;10(1):4359..

PDF Project Pubmed

AK Khoshal, B Novak, PGP Martin, T Jenkins, M Neves, G Schatzmayr, IP Oswald, P Pinton (2019). Co-occurrence of DON and Emerging Mycotoxins in Worldwide Finished Pig Feed and Their Combined Toxicity in Intestinal Cells. Toxins (Basel). 2019 Dec 11;11(12):727..

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D Hermier, N Guelzim, PG Martin, JF Huneau, V Mathe, A Quignard-Boulange, F Lasserre, F Mariotti (2017). NO synthesis from arginine is favored by alpha-linolenic acid in mice fed a high-fat diet. Amino Acids. 2016 Sep;48(9):2157-68..

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S Ducheix, A Montagner, A Polizzi, F Lasserre, M Regnier, A Marmugi, F Benhamed, J Bertrand-Michel, L Mselli-Lakhal, N Loiseau, PG Martin, JM Lobaccaro, L Ferrier, C Postic, H Guillou (2017). Dietary oleic acid regulates hepatic lipogenesis through a liver X receptor-dependent signaling. PLoS One. 2017 Jul 21;12(7):e0181393..

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PF Roux, L Fresard, M Boutin, S Leroux, C Klopp, A Djari, D Esquerre, PG Martin, T Zerjal, D Gourichon, F Pitel, S Lagarrigue (2016). The Extent of mRNA Editing Is Limited in Chicken Liver and Adipose, but Impacted by Tissular Context, Genotype, Age, and Feeding as Exemplified with a Conserved Edited Site in COG3.. G3 (Bethesda). 2015 Dec 4;6(2):321-35..

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M SanCristobal, F Rohart, C Lascor, M Bouffaud, L Trouilh, PG Martin, Y Lippi, T Tribout, T Faraut, MJ Mercat, D Milan, L Liaubet (2016). Exploring transcriptomic diversity in muscle revealed that cellular signaling pathways mainly differentiate five Western porcine breeds.. BMC Genomics. 2015 Dec 12;16:1055..

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C Meslin, C Desert, I Callebaut, A Djari, C Klopp, F Pitel, S Leroux, P Martin, P Froment, E Guilbert, F Gondret, S Lagarrigue, P Monget (2015). Expanding Duplication of Free Fatty Acid Receptor-2 (GPR43) Genes in the Chicken Genome.. Genome Biol Evol. 2015 Apr 24;7(5):1332-48..

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B Stadelmayer, G Micas, A Gamot, P Martin, N Malirat, S Koval, R Raffel, B Sobhian, D Severac, S Rialle, H Parrinello, O Cuvier, M Benkirane (2015). Integrator complex regulates NELF-mediated RNA polymerase II pause/release and processivity at coding genes.. Nat Commun. 2014 Nov 20;5:5531..

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V Voillet, M SanCristobal, Y Lippi, PG Martin, N Iannuccelli, C Lascor, F Vignoles, Y Billon, L Canario, L Liaubet (2015). Muscle transcriptomic investigation of late fetal development identifies candidate genes for piglet maturity.. BMC Genomics. 2014 Sep 17;15:797..

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T Cadoudal, M Buleon, C Sengenes, G Diene, F Desneulin, C Molinas, S Eddiry, F Conte-Auriol, D Daviaud, PG Martin, A Bouloumie, JP Salles, M Tauber, P Valet (2015). Impairment of adipose tissue in Prader-Willi syndrome rescued by growth hormone treatment.. Int J Obes (Lond). 2014 Sep;38(9):1234-40..

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S Labialle, V Marty, ML Bortolin-Cavaille, M Hoareau-Osman, JP Pradere, P Valet, PG Martin, J Cavaille (2015). The miR-379/miR-410 cluster at the imprinted Dlk1-Dio3 domain controls neonatal metabolic adaptation.. EMBO J. 2014 Oct 1;33(19):2216-30..

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N Moussaoui, V Braniste, A Ait-Belgnaoui, M Gabanou, S Sekkal, M Olier, V Theodorou, PG Martin, E Houdeau (2015). Changes in intestinal glucocorticoid sensitivity in early life shape the risk of epithelial barrier defect in maternal-deprived rats.. PLoS One. 2014 Feb 20;9(2):e88382..

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A Marmugi, F Lasserre, D Beuzelin, S Ducheix, L Huc, A Polizzi, M Chetivaux, T Pineau, P Martin, H Guillou, L Mselli-Lakhal (2014). Adverse effects of long-term exposure to bisphenol A during adulthood leading to hyperglycaemia and hypercholesterolemia in mice.. Toxicology. 2014 Nov 5;325:133-43..

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J Liang, L Lacroix, A Gamot, S Cuddapah, S Queille, P Lhoumaud, P Lepetit, PG Martin, J Vogelmann, F Court, M Hennion, G Micas, S Urbach, O Bouchez, M Nollmann, K Zhao, E Emberly, O Cuvier (2014). Chromatin immunoprecipitation indirect peaks highlight long-range interactions of insulator proteins and Pol II pausing.. Mol Cell. 2014 Feb 20;53(4):672-81..

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S Ducheix, A Montagner, A Polizzi, F Lasserre, A Marmugi, J Bertrand-Michel, N Podechard, Saati Al, M Chetiveaux, S Baron, J Boue, G Dietrich, L Mselli-Lakhal, P Costet, JM Lobaccaro, T Pineau, V Theodorou, C Postic, PG Martin, H Guillou (2014). Essential fatty acids deficiency promotes lipogenic gene expression and hepatic steatosis through the liver X receptor.. J Hepatol. 2013 May;58(5):984-92..

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BB Roques, J Leghait, MZ Lacroix, F Lasserre, T Pineau, C Viguie, PG Martin (2013). The nuclear receptors pregnane X receptor and constitutive androstane receptor contribute to the impact of fipronil on hepatic gene expression linked to thyroid hormone metabolism.. Biochem Pharmacol. 2013 Oct 1;86(7):997-1039..

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S Ducheix, N Podechard, F Lasserre, A Polizzi, A Pommier, S Murzilli, Lisio Di, S D'Amore, J Bertrand-Michel, A Montagner, T Pineau, N Loiseau, JM Lobaccaro, PG Martin, H Guillou (2013). A systems biology approach to the hepatic role of the oxysterol receptor LXR in the regulation of lipogenesis highlights a cross-talk with PPARalpha.. Biochimie. 2013 Mar;95(3):556-67..

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BB Roques, MZ Lacroix, S Puel, V Gayrard, N Picard-Hagen, I Jouanin, E Perdu, PG Martin, C Viguie (2012). CYP450-dependent biotransformation of the insecticide fipronil into fipronil sulfone can mediate fipronil-induced thyroid disruption in rats.. Toxicol Sci. 2012 May;127(1):29-41..

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A Marmugi, S Ducheix, F Lasserre, A Polizzi, A Paris, N Priymenko, J Bertrand-Michel, T Pineau, H Guillou, PG Martin, L Mselli-Lakhal (2012). Low doses of bisphenol A induce gene expression related to lipid synthesis and trigger triglyceride accumulation in adult mouse liver.. Hepatology. 2012 Feb;55(2):395-407..

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M Foucaud-Vignault, Z Soayfane, C Menez, J Bertrand-Michel, PG Martin, H Guillou, X Collet, A Lespine (2012). P-glycoprotein dysfunction contributes to hepatic steatosis and obesity in mice.. PLoS One. 2011;6(9):e23614..

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N Guelzim, F Mariotti, PG Martin, F Lasserre, T Pineau, D Hermier (2012). A role for PPARalpha in the regulation of arginine metabolism and nitric oxide synthesis.. Amino Acids. 2011 Oct;41(4):969-79..

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S Ducheix, JM Lobaccaro, PG Martin, H Guillou (2012). Liver X Receptor: an oxysterol sensor and a major player in the control of lipogenesis.. Chem Phys Lipids. 2011 Sep;164(6):500-14..

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R Solinhac, F Mompart, P Martin, D Robelin, P Pinton, E Iannuccelli, Y Lahbib-Mansais, IP Oswald, M Yerle-Bouissou (2011). Transcriptomic and nuclear architecture of immune cells after LPS activation.. Chromosoma. 2011 Oct;120(5):501-20..

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N Guelzim, JF Huneau, V Mathe, A Quignard-Boulange, PG Martin, D Tome, D Hermier (2011). Consequences of PPAR(alpha) Invalidation on Glutathione Synthesis: Interactions with Dietary Fatty Acids.. PPAR Res. 2011;2011:256186..

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J Chamouton, F Hansmannel, JA Bonzo, MC Clemencet, G Chevillard, M Battle, P Martin, T Pineau, S Duncan, FJ Gonzalez, N Latruffe, S Mandard, V Nicolas-Frances (2011). The Peroxisomal 3-keto-acyl-CoA thiolase B Gene Expression Is under the Dual Control of PPARalpha and HNF4alpha in the Liver.. PPAR Res. 2010;2010:352957..

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P Blavy, F Gondret, H Guillou, S Lagarrigue, PG Martin, Milgen van, O Radulescu, A Siegel (2011). A minimal model for hepatic fatty acid balance during fasting: application to PPAR alpha-deficient mice.. J Theor Biol. 2009 Nov 21;261(2):266-78..

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A Montfort, PG Martin, T Levade, H Benoist, B Segui (2010). FAN (factor associated with neutral sphingomyelinase activation), a moonlighting protein in TNF-R1 signaling.. J Leukoc Biol. 2010 Nov;88(5):897-903..

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S Dejean, PG Martin, A Baccini, P Besse (2010). Clustering time-series gene expression data using smoothing spline derivatives.. EURASIP J Bioinform Syst Biol. 2007:70561..

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C Dray, C Debard, J Jager, E Disse, D Daviaud, P Martin, C Attane, E Wanecq, C Guigne, F Bost, JF Tanti, M Laville, H Vidal, P Valet, I Castan-Laurell (2010). Apelin and APJ regulation in adipose tissue and skeletal muscle of type 2 diabetic mice and humans.. Am J Physiol Endocrinol Metab. 2010 Jun;298(6):E1161-9..

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H Guillou, D Zadravec, PG Martin, A Jacobsson (2010). The key roles of elongases and desaturases in mammalian fatty acid metabolism: Insights from transgenic mice.. Prog Lipid Res. 2010 Apr;49(2):186-99..

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M Giantin, RM Lopparelli, V Zancanella, PG Martin, A Polizzi, G Gallina, F Gottardo, C Montesissa, L Ravarotto, T Pineau, M Dacasto (2010). Effects of illicit dexamethasone upon hepatic drug metabolizing enzymes and related transcription factors mRNAs and their potential use as biomarkers in cattle.. J Agric Food Chem. 2010 Jan 27;58(2):1342-9..

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V Braniste, A Jouault, E Gaultier, A Polizzi, C Buisson-Brenac, M Leveque, PG Martin, V Theodorou, J Fioramonti, E Houdeau (2010). Impact of oral bisphenol A at reference doses on intestinal barrier function and sex differences after perinatal exposure in rats.. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):448-53..

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A Montfort, Badts de, V Douin-Echinard, PG Martin, J Iacovoni, C Nevoit, N Therville, V Garcia, MA Bertrand, MH Bessieres, MC Trombe, T Levade, H Benoist, B Segui (2009). FAN stimulates TNF(alpha)-induced gene expression, leukocyte recruitment, and humoral response.. J Immunol. 2009 Oct 15;183(8):5369-78..

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A Eveillard, L Mselli-Lakhal, A Mogha, F Lasserre, A Polizzi, JM Pascussi, H Guillou, PG Martin, T Pineau (2009). Di-(2-ethylhexyl)-phthalate (DEHP) activates the constitutive androstane receptor (CAR): a novel signalling pathway sensitive to phthalates.. Biochem Pharmacol. 2009 Jun 1;77(11):1735-46..

Project Project Pubmed

A Eveillard, F Lasserre, Tayrac de, A Polizzi, S Claus, C Canlet, L Mselli-Lakhal, G Gotardi, A Paris, H Guillou, PG Martin, T Pineau (2009). Identification of potential mechanisms of toxicity after di-(2-ethylhexyl)-phthalate (DEHP) adult exposure in the liver using a systems biology approach.. Toxicol Appl Pharmacol. 2009 May 1;236(3):282-92..

Project Project Pubmed

Cao Le, PG Martin, C Robert-Granie, P Besse (2009). Sparse canonical methods for biological data integration: application to a cross-platform study.. BMC Bioinformatics. 2009 Jan 26;10:34..

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M Cantiello, M Giantin, M Carletti, RM Lopparelli, F Capolongo, F Lasserre, E Bollo, C Nebbia, PG Martin, T Pineau, M Dacasto (2009). Effects of dexamethasone, administered for growth promoting purposes, upon the hepatic cytochrome P450 3A expression in the veal calf.. Biochem Pharmacol. 2009 Feb 1;77(3):451-63..

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H Guillou, PG Martin, T Pineau (2008). Transcriptional regulation of hepatic fatty acid metabolism.. Subcell Biochem. 2008;49:3-47..

Project Project Pubmed

M Cantiello, M Carletti, M Dacasto, PG Martin, T Pineau, F Capolongo, G Gardini, C Nebbia (2008). Cytochrome P450 inhibition profile in liver of veal calves administered a combination of 17beta-estradiol, clenbuterol, and dexamethasone for growth-promoting purposes.. Food Chem Toxicol. 2008 Aug;46(8):2849-55..

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D Bellocq, J Molina, E Rathahao, C Canlet, S Tache, PG Martin, F Pierre, A Paris (2008). High potency of bioactivation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mouse colon epithelial cells with Apc(Min) mutation.. Mutat Res. 2008 May 31;653(1-2):34-43..

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M Giantin, M Carletti, F Capolongo, S Pegolo, RM Lopparelli, F Gusson, C Nebbia, M Cantiello, P Martin, T Pineau, M Dacasto (2008). Effect of breed upon cytochromes P450 and phase II enzyme expression in cattle liver.. Drug Metab Dispos. 2008 May;36(5):885-93..

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V Petit, L Arnould, P Martin, MC Monnot, T Pineau, P Besnard, I Niot (2008). Chronic high-fat diet affects intestinal fat absorption and postprandial triglyceride levels in the mouse.. J Lipid Res. 2007 Feb;48(2):278-87..

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Y Lecarpentier, X Krokidis, P Martin, T Pineau, JL Hebert, J Quillard, M Cortes-Morichetti, C Coirault (2008). Increased entropy production in diaphragm muscle of PPAR alpha knockout mice.. J Theor Biol. 2008 Jan 7;250(1):92-102..

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A Baccini, P Besse, S Déjean, **PGP Martin**, C Robert-Granié, M SanCristobal (2008). Stratégies pour l'analyse statistique de données transcriptomiques. J-SFdS 2008 Jan;146(12):5-44..

PDF Project

I Gonzalez, S Déjean, **PGP Martin**, A Baccini (2008). CCA: An R Package to Extend Canonical Correlation Analysis. J Stat Soft. 2008 Jan;23(12):1-14..

PDF Project DOI

PH Villard, S Caverni, A Baanannou, A Khalil, PG Martin, C Penel, T Pineau, E Seree, Y Barra (2007). PPARalpha transcriptionally induces AhR expression in Caco-2, but represses AhR pro-inflammatory effects.. Biochem Biophys Res Commun. 2007 Dec 28;364(4):896-901..

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N Loiseau, L Debrauwer, T Sambou, S Bouhet, JD Miller, PG Martin, JL Viadere, P Pinton, O Puel, T Pineau, J Tulliez, P Galtier, IP Oswald (2007). Fumonisin B1 exposure and its selective effect on porcine jejunal segment: sphingolipids, glycolipids and trans-epithelial passage disturbance.. Biochem Pharmacol. 2007 Jun 30;74(1):144-52..

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PG Martin, H Guillou, F Lasserre, S Dejean, A Lan, JM Pascussi, M Sancristobal, P Legrand, P Besse, T Pineau (2007). Novel aspects of PPARalpha-mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study.. Hepatology. 2007 Mar;45(3):767-77..

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MF Bassissi, M Alvinerie, PG Martin, B Perret, A Lespine (2006). Influence of dyslipidemia on moxidectin distribution in plasma lipoproteins and on its pharmacokinetics.. Pharm Res. 2006 Nov;23(11):2672-80..

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PG Martin, F Lasserre, C Calleja, Es Van, A Roulet, D Concordet, M Cantiello, R Barnouin, B Gauthier, T Pineau (2006). Transcriptional modulations by RXR agonists are only partially subordinated to PPARalpha signaling and attest additional, organ-specific, molecular cross-talks.. Gene Expr. 2005;12(3):177-92..

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C Gondcaille, M Depreter, S Fourcade, MR Lecca, S Leclercq, PG Martin, T Pineau, F Cadepond, M ElEtr, N Bertrand, A Beley, S Duclos, Craemer De, F Roels, S Savary, M Bugaut (2005). Phenylbutyrate up-regulates the adrenoleukodystrophy-related gene as a nonclassical peroxisome proliferator.. J Cell Biol. 2005 Apr 11;169(1):93-104..

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JM Pascussi, A Robert, M Nguyen, O Walrant-Debray, M Garabedian, P Martin, T Pineau, J Saric, F Navarro, P Maurel, MJ Vilarem (2005). Possible involvement of pregnane X receptor-enhanced CYP24 expression in drug-induced osteomalacia.. J Clin Invest. 2005 Jan;115(1):177-86..

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Jossic-Corcos Le, S Duclos, LC Ramirez, I Zaghini, G Chevillard, P Martin, T Pineau, P Bournot (2004). Effects of peroxisome proliferator-activated receptor alpha activation on pathways contributing to cholesterol homeostasis in rat hepatocytes.. Biochim Biophys Acta. 2004 Jul 5;1683(1-3):49-58..

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G Chevillard, MC Clemencet, P Etienne, P Martin, T Pineau, N Latruffe, V Nicolas-Frances (2004). Tissue-specific expression of two peroxisomal 3-ketoacyl-CoA thiolase genes in wild and PPAR alpha-null mice and induction by fenofibrate.. Adv Exp Med Biol. 2003;544:55-6..

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M Bugaut, S Fourcade, C Gondcaille, F Gueugnon, M Depreter, F Roels, A Netik, J Berger, P Martin, T Pineau, F Cadepond, Etr El, S Savary (2004). Pharmacological induction of redundant genes for a therapy of X-ALD: phenylbutyrate and other compounds.. Adv Exp Med Biol. 2003;544:281-91..

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G Chevillard, MC Clemencet, P Etienne, P Martin, T Pineau, N Latruffe, V Nicolas-Frances (2004). Molecular cloning, gene structure and expression profile of two mouse peroxisomal 3-ketoacyl-CoA thiolase genes.. BMC Biochem. 2004 Mar 25;5:3..

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H Guillou, P Martin, S Jan, S D'Andrea, A Roulet, D Catheline, V Rioux, T Pineau, P Legrand (2004). Comparative effect of fenofibrate on hepatic desaturases in wild-type and peroxisome proliferator-activated receptor alpha-deficient mice.. Lipids. 2002 Oct;37(10):981-9..

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G Lambert, MJ Amar, P Martin, J Fruchart-Najib, B Foger, RD Shamburek, HB Brewer, S Santamarina-Fojo (2000). Hepatic lipase deficiency decreases the selective uptake of HDL-cholesteryl esters in vivo.. J Lipid Res. 2000 May;41(5):667-72..

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