S Ducheix

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• Dietary oleic acid regulates hepatic lipogenesis through a liver X receptor-dependent signaling
• Adverse effects of long-term exposure to bisphenol A during adulthood leading to hyperglycaemia and hypercholesterolemia in mice.
• Essential fatty acids deficiency promotes lipogenic gene expression and hepatic steatosis through the liver X receptor.
• A systems biology approach to the hepatic role of the oxysterol receptor LXR in the regulation of lipogenesis highlights a cross-talk with PPARalpha.
• Low doses of bisphenol A induce gene expression related to lipid synthesis and trigger triglyceride accumulation in adult mouse liver.
• Liver X Receptor: an oxysterol sensor and a major player in the control of lipogenesis.